When you get a rash from poison ivy, it’s a reaction to an oily, sticky resin called urushiol. It’s estimated that nearly 90% of people are allergic to urushiol, which is in every part of the plant, from root to fruit. Any contact with the plant can leave resin on your skin and trigger a rash. You can even break out after touching something that touched poison ivy, like a gardening tool or a pet. A poison ivy reaction usually appears 12 to 48 hours after contact with the plant. But the timeframe can vary. Some people might notice a rash sooner, while it may take longer to pop up for others. Now, the good news: You’ve got options when it comes to limiting the symptoms of a poison ivy rash. Here’s what you can try: 1️⃣Clean the area immediately 2️⃣Apply topical creams 3️⃣Take antihistamines 4️⃣Soak in medicated baths 5️⃣Use cold compresses 6️⃣Protect your skin. Covering a poison ivy rash with light bandages or clothing (like long-sleeved shirts) can help keep your skin clean to prevent additional irritation as it recovers. Make an appointment with a healthcare provider if you have: -Severe, extensive and widespread rash -A rash on your face, including swelling around the eyelids -Rash accompanied by fever, chills or signs of infection They may be able to prescribe you stronger medication to lessen symptoms or offer other advice to find relief